Pipeline

Pipeline

Pioneering RNA Therapeutics for Metabolic and Neurological Disorders

Canary Cure is at the forefront of medical innovation, leveraging the power of RNA therapeutics to revolutionize the treatment landscape for rare diseases and metabolic disorders. Our cutting-edge pipeline harnesses the potential of RNA to precisely target the underlying genetic causes of these debilitating conditions, offering a new hope for patients and their families.
Through our innovative RNA-based approaches, we aim to not only halt disease progression but also restore function and improve quality of life for those affected by some of the most challenging medical conditions. Our commitment to developing targeted, effective therapies is driven by a deep understanding of the unmet needs of patients and a passion for scientific discovery.
Obesity and Metabolic Diseases
We are leveraging the power of RNA therapeutics to address the root causes of obesity and metabolic disorders by:
By targeting these pathways, we strive to provide safe and effective treatment options for individuals struggling with obesity, including children with rare forms of the disease.
Treating the Root Causes of Obesity
At the forefront of our pipeline are novel treatments for severe obesity and Leptin Deficiency Disorder (LDD), a rare form of childhood obesity. By addressing both energy expenditure and appetite control, Canary’s proprietary combinatorial therapy holds the potential of overcoming limitation of single-target approaches and achieve more effective and sustained weight loss. Using gene modulating approaches, our goal is metabolic stability and long-term health.
Developing World’s First Treatment for 4H Leukodystrophy
Primarily a pediatric disease, this rare genetic disorder affects the nervous system causing developmental delays, motor difficulties, endocrine issues and other abnormalities. Using mRNA encased in LNP that delivers functional gene directly to affected cells. The goals is to enable the production of healthy protein to halt the progression of the disease and potentially restore function.
Companion Diagnostics for Early Detection and Intervention
In conjunction with our therapeutic efforts, we are also developing novel companion diagnostics that leverage miRNA biomarkers sourced from partner human clinical trials. These diagnostics hold the potential to detect complex diseases and cancers at their earliest stages, enabling timely intervention and maximizing the efficacy of our therapeutic approaches.
Partnering for Progress
We are dedicated to fostering collaborative partnerships that accelerate the development of our transformative therapies. We regularly engage with key partners to share pipeline updates and explore new avenues for therapeutic advancement.
Our Vision: Preserving Human Life
At the heart of our endeavors lies an unwavering commitment to preserving human life. Our pipeline of vectorized gene therapies represents a beacon of hope for individuals facing CNS proteinopathies and rare neurological diseases. We are driven by the unwavering belief that these groundbreaking therapies have the potential to halt disease progression, restore function, and transform the lives of countless individuals.
Canary DigiGENE miRNA Diagnostic overview
Our point of care diagnostic platform uses Al to read miRNA expression patterns in complex diseases at the earliest stages.
Studies have shown a clear distinction in miRNA expression patterns between disease sample and normal healthy samples. This is a heat map of four breast cancer patients showing separation of miRNA expression profiles in tumors and normal tissues.
Canary Pipeline Overview
Therapeutic Pipeline
Canary’s Obesity & Metabolic Disorder Pipeline
How it Works

“Lab-on-a-Chip” with Cloud-based Analytics

DigiGENE™ Molecular Point-of-Care Test Platform

One Step Nucleic Acid Amplification Test