Modality
A multimodal siRNA / mRNA approach focused on peripheral adipose biology and metabolic signaling.
METABOLIC RESTORATION / CCT-987
Prader-Willi syndrome
Understanding the condition, Canary’s research focus, and resources for individuals and families.
UNDERSTANDING PWS
A complex, lifelong genetic condition.
Prader-Willi syndrome (PWS) is a rare genetic condition associated with altered function of genes on chromosome 15. It can affect appetite regulation, growth, muscle tone, learning, and behavior.
Infants often experience low muscle tone and feeding difficulties. Later, persistent hunger—called hyperphagia—can become a major challenge. Lower energy expenditure and reduced muscle mass can add to difficulties with weight management.
Symptoms and support needs vary. Care often involves several specialties and ongoing support for individuals, families, and caregivers.
Learn more: PWSA USA’s overview of Prader-Willi syndrome.
CANARY’S RESEARCH FOCUS
CCT-987: metabolic restoration.
Canary’s CCT-987 program investigates functional adipose rescue and metabolic restoration for Prader-Willi syndrome and related metabolic disease.
Development focus
Functional adipose measurements and cell-resolved expression, alongside an IND-enabling in vivo package.
Research objective
Evaluate whether the proposed approach can restore aspects of adipose function. Benefit in people with PWS has not been established.
CCT-987 is investigational and is not an approved treatment for Prader-Willi syndrome. Its development follows a rare-disease research path.
View the CCT-987 pipeline overviewPATIENTS, FAMILIES & CAREGIVERS
Information and community support.
Prader-Willi Syndrome Association | USA
PWSA USA provides education, family support, advocacy, and research resources for the Prader-Willi syndrome community.
Visit PWSA USAThis external resource is provided for information. The link does not imply a partnership or endorsement.